Hi-C Seq

 Hi-C sequencing is high‐throughput chromosome conformation capture technique to analyze spatial genome organization and map higher‐order chromosome folding and topological associated domains.

Hi-C quantifies the number of interactions between genomic loci that are closely located in 3-D space, but may be separated by many nucleotides in the linear genome.

Hi-C allows quantification of interactions between all possible pairs of DNA fragments simultaneously.